The present invention has an object to provide a novel agent for anti-neurodegenerative diseases and solves the object by providing an agent for anti-neurodegenerative diseases containing, as an effective ingredient, the compound(s) represented by the following General formula 1: wherein in General formula 1, R 1 through R 3 independently represent a hydrogen atom or an appropriate substituent； Z 1 represents a heterocyclic ring and Z 2 represents the same or different heterocyclic or aromatic ring as in Z 1 , wherein the heterocyclic and aromatic rings optionally have a substituent； o represents an integer of 0, 1 or 2； p represents an integer of 0 or 1, with the proviso that p is 1 when o is 0 or 2, and p is 0 when o is 1； R 1 and R 2 do not exist when o is 0, while, when p is 0, R 3 does not exist and the binding between the carbon atom to which R 2 binds and Z 2 is a single bond； X 1 - represents an appropriate counter anion and q represents an integer of 1 or 2.本發明以提供新穎的抗神經變性疾病用劑為課題，且藉由提供以下述一般式1表示的化合物為有效成分的抗神經變性疾病用劑達成課題。一般式1中R1至R3係表示分別獨立的氫原子或適宜的取代基，Z1係表示雜環，Z2係表示與Z1相同或相異的雜環或芳香環，該等雜環及芳香環亦可具有取代基。o係表示0、1或2中任一個整數，p係表示0或1中任一個整數，當o為0或2時，p為1，o為1時，p為0。o為0時，R1及R2不存在，p為0時，R3不存在，鍵結於R2上的碳原子與Z2形成單鍵。X1-係表示適宜的反陰離子(counter anion)，q係表示1或2中任一個整數。
