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CROSSLINKED POLYMERS
专利权人:
ЮСВ ЛИМИТЕД (IN)
发明人:
САТЕ Дхананджай Говинд (IN),МОНДКАР Хариш Кашинат (IN),РАО Мантрипрагада Нараян (IN),ПАТИЛ Самадхан Даулат (IN),ДЖАДХАВ Танаджи Шамрао (IN),ОМРАЙ Ашок (IN),ЧУДХАРИ Варша Шашанк (IN),БХИДЕ Йогеш Шарад
申请号:
RU2011112694/15
公开号:
RU2011112694A
申请日:
2009.09.02
申请国别(地区):
RU
年份:
2012
代理人:
摘要:
1. A pharmaceutical composition comprising a bile acid sequestrant formed by wet granulation and at least one pharmaceutical excipient, wherein the composition is free of reduced sugar. ! 2. The composition according to claim 1, additionally containing an additional agent selected from biguanide, sulfonylurea, thiazolidinedione, dipeptidyl peptidase IV inhibitor, alpha glucosidase inhibitor, meglitinides, fibrates and statins. ! 3. The composition according to claim 1, where the sequestrant of bile acids is selected from the group consisting of wheel magnam, cholestyramine, colestipol, sevelamer and colestimide. ! 4. The composition according to claim 3, which is in the form of granules, tablets or capsules. ! 5. The composition according to claim 1, in which the sequestrant of bile acids is an alkyl crosslinked polymer. ! 6. A pharmaceutical composition comprising a spinner formed by wet granulation together with at least one pharmaceutically acceptable excipient, wherein the particles of spinel are spherical or globular in shape. ! 7. The composition according to claim 6, in which the wheel loader is present in an amount in the range from about 50% to about 85%, based on the weight of the total composition. ! 8. The composition according to claim 6, which contains no more than 90 wt.% Hydrated wheel lovelam. ! 9. The composition according to claim 7 or claim 8, which is free from restored sugars. ! 10. The composition according to claim 9, where the composition is in the form of granules, tablets or capsules. ! 11. The composition according to claim 6, where the dosage at one time is in the range from about 500 mg to about 800 mg of wheel-loam. ! 12. The composition according to claim 6, where the said wheel1. Фармацевтическая композиция, содержащая формуемый в результате влажного гранулирования секвестрант желчных кислот и, по меньшей мере, один фармацевтический эксципиент, где композиция свободна от восстановленного сахара. ! 2. Композиция по п.1, дополнительно
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