Water-soluble film or solid gel with healing activity comprising: . a) between 25 and 60% by weight of sodium alginate, as main filmogenous substance, . b) between 0.1 and 20% by weight of microcrystalline cellulose over the total weight of the film, . c) between 0.1 and 25% by weight of vegetable proteins, . d) at least one glycosaminoglycan and/or galactosaminoglycan sulphate of the natural type, as active ingredient with healing activity and a device for medical use in particular for topical applications, containing said water-soluble film. This device is in particular suitable for covering sores and wounds, even large ones, protecting them from the external environment, continuously providing glycosaminoglycan sulphate and/or galactosaminoglycan sulphate of the natural type in the area of the damaged skin. An organic hydroxy acid can be added to accelerate the wound healing.