Suppression of bone loss by introducing FoxP3+ CD8 T-cells (TcREG)

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专利权人:

发明人:

Rajeev Aurora,Zachary Buchwald

申请号：

US15052793

公开号：

US09713633B1

申请日:

2016.02.24

申请国别(地区):

US

年份:

2017

代理人:

摘要：

Systems and methods for inhibiting bone loss using FoxP3+ CD8 T-cells (TcREG). Osteoclasts are induced to produce FoxP3+ CD8 T-cells (TcREG) through introduction of a low-dose of a RANK agonist such as RANKL. The RANKL was found to best work when provided in accordance with a schedule resulting in a pulsed administration.

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中国工程科技知识中心

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http://www.ckcest.cn/home/