Evan Schauer,Miroslav Baudys,Brian C. Varnum,Christopher W. Kaplan,Randal H. Eckert,Jay Turetzky,Angela Soriaga
申请号：
US16604130
公开号：
US20200276103A1
申请日:
2018.04.12
申请国别(地区):
US
年份:
2020
代理人:
摘要：
In various embodiments a dental varnish system having improved peptide release and fluoride release properties is provided. In various embodiments a dental varnish system that provides release of an antimicrobial peptide, or specifically targeted antimicrobial peptide (STAMP), e.g., the peptide C16G2, is provided, with or without a fluoride. In various embodiments, a dental varnish system that provides release of a fluoride, with or without an antimicrobial peptide or STAMP is provided. In certain embodiments the dental varnish system comprises a first component that is a dry powder, said first component comprising a an antimicrobial peptide, with or without a fluoride, and a bulking agent, and a second component that is a fluid, said second component comprising a varnish solution, where combination of said first component with said second component provides a varnish formulation for application to the surface of a tooth.
