Ariane VOLKMANN,Robin STEIGERWALD,Ulrike DIRMEIER,Benoit Christophe Stephan CALLENDRET,Macaya Julie DOUOGUIH,Lucy A. WARD
申请号：
US15508288
公开号：
US20170340721A1
申请日:
2015.09.03
申请国别(地区):
US
年份:
2017
代理人:
摘要：
Compositions and methods are described for generating an improved effective immune response against an immunogen in humans. The enhanced immune response, is obtained by using an MVA vector as a prime and an adenovirus vector as a boost and is characterized by a high level of antibody response specific to the immunogen, and an enhanced cellular immune response. The compositions and methods can be used to provide a protective immunity against a disease, such as an infection of one or more subtypes of Ebola and Marburg filoviruses, in humans.
