USE OF VECTORS EXPRESSING INTRACELLULAR POLYNUCLEOTIDE BINDING PROTEINS AS ADJUVANTS

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专利权人:

CELLECTIS

发明人:

LJUNGBERG, KARL,LLADSER, ALVARO,KIESSLING, ROLF

申请号：

EP09843431

公开号：

EP2419125A4

申请日:

2009.10.22

申请国别(地区):

EP

年份:

2013

代理人:

摘要：

An object of the invention is to provide a vaccine adjuvant that is comprised of a vector capable of expressing a polynucleotide binding protein in excess of levels already present in cells. Expression of the polynucleotide binding protein initiates intracellular pathways that lead to expression of type 1 interferons. In concert with expression of type 1 interferons, other cytokines are expressed, and the immune response to vaccine antigens given with the adjuvant is enhanced.

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