David Y. Jackson,Michael Nathaniel Alonso,Arthur Lee
申请号:
US16723276
公开号:
US20200108151A1
申请日:
2019.12.20
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The invention provides an immunoconjugate comprising an antibody construct which includes an antigen binding domain and an Fc domain, an adjuvant moiety, and a linker, wherein each adjuvant moiety is covalently bonded to the antibody via the linker which comprises an ethylene glycol group or glycine residue. Methods for treating cancer with the immunoconjugates of the invention are also described.