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System and methods for deriving gene signature biomarkers of response to PD-1 antagonists
专利权人:
Merck Sharp & Dohme Corp.
发明人:
Ayers, Mark D.,Loboda, Andrey,Lunceford, Jared K.,McClanahan, Terrill K.,Murphy, Erin E.,Nebozhyn, Michael
申请号:
AU2020204557
公开号:
AU2020204557A1
申请日:
2020.07.08
申请国别(地区):
AU
年份:
2020
代理人:
摘要:
#$%^&*AU2020204557A120200730.pdf#####SYSTEM AND METHODS FOR DERIVING GENE SIGNATURE BIOMARKERS OF RESPONSE TO PD-i ANTAGONISTS ABSTRACT A gene expression platform, which is a combination of a set of genes that are correlated with response to a PD-i antagonist in multiple tumor types and a normalization gene set, is disclosed. A method and system of using the gene expression platform to derive gene signature biomarkers of anti-tumor response to a PD-i antagonist and to test patient samples for predictive gene signature biomarkers are also disclosed. AH26(25373730_1):RTK
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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