The present invention relates to a medical image compression system and method suitable for visually lossless compression and, more specifically, to a medical image compression system and method capable of obtaining medical images at a high enough compression ratio while preventing loss in information needed to diagnose. The medical image compression system according to one example of the present invention comprises: a storage unit for storing initial learning data and an equation regarding an optimal compression ratio to compress a medical image to be diagnosed at an optimal ratio; a processor for obtaining an optimal compression ratio of the medical image to be diagnosed by using the stored initial learning data and the equation for the optimal compression ratio; and for compressing the medical image to be diagnosed at the optimal compression ratio obtained by the computation unit.