Chen, Xi,Fan, Pingchen,Li, Yandong,Powers, Jay P.,Malathong, Viengkham,Punna, Sreenivas,Tanaka, Hiroko,Zhang, Penglie,Dragoli, Dean
申请号:
AU2013355054
公开号:
AU2013355054B2
申请日:
2013.12.06
申请国别(地区):
AU
年份:
2017
代理人:
摘要:
Compounds are provided that act as potent antagonists of the CCR1 receptor, and have in vivo anti-inflammatory activity. The compounds are diazole lactam derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR1-mediated disease, and as controls in assays for the identification of competitive CCR1 antagonists.