NIKOLAI TANKOVICH,Alexander Kharazi,Alexei Lukashev,Yuri Kudinov
申请号:
US14138078
公开号:
US20160143950A1
申请日:
2013.12.22
申请国别(地区):
US
年份:
2016
代理人:
摘要:
Therapeutic stem cells and methods for their use and manufacture. Stem cells are produced under conditions in which the stem cells are exposed to at least one environmental factor, including decreased oxygen tension. The environmental factors and culture conditions of the invention produce stem cells having an enhanced therapeutic ability and enhanced proliferation in culture. Stem cells of the invention retain their plasticity through a higher number of cell passages relative to know methods of stem cell culture. The invention also contemplates the use of such stem cells in the treatment of neurodegenerative disorders including Alzheimers disease and stroke.