YU, CHENG-DER, TONY T,WANG, CHENG-CHI, IRENE I,LEE, WEI-HAN,LIN, YU-CHEN,LIN, YU-HSIN, TOM T,CHEN, I-JU,.遊丞德,.王正琪,李威漢,林侑蓁,.林雨新,陳怡如
申请号：
HK16109563.0
公开号：
HK1221476A
申请日:
2016.08.10
申请国别(地区):
HK
年份:
2017
代理人:
摘要：
The invention encompasses therapeutic compositions including Globo H-KLH conjugates and/or therapeutic antibodies as well as methods of making and using the same to treat proliferative diseases such as cancer. The therapeutic conjugates include an antigen linked to a carrier. In particular the therapeutic conjugates include a Globo H moiety and a KLH moiety and/or a derivatized KLH moiety subunit optionally linked via a linker. The therapeutic compositions are in part envisaged to act as cancer vaccines for boosting the body's natural ability to protect itself, through the immune system from dangers posed by damaged or abnormal cells such as cancer cells. An effective immune response is one that reduces the severity of disease, including but not limited to, prevention of disease, delay in onset of disease, decreased severity of symptoms, decreased morbidity and delayed mortality.
