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Third Generation Taxoids and Methods of Using Same
专利权人:
The Research Foundation for the State University of New York
发明人:
Iwao OJIMA,Changwei WANG,Xin WANG
申请号:
US15740859
公开号:
US20180194744A1
申请日:
2016.07.01
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The invention includes taxoid compounds represented by the formula:wherein: R1 represents a methyl group or a fluorine; R2 represents an alkyl or alkenyl group having one to six carbon atoms; or a cycloalkyl or cycloalkenyl group having three to seven ring carbon atoms; R3 represents an alkyl, alkenyl, dialkylamino, alkylamino, or alkoxy group having one to six carbon atoms; a cycloalkyl or cycloalkenyl group having three to seven ring carbon atoms; an aryl group having six to eighteen ring carbon atoms; or a heteroaryl group having three to seventeen ring carbon atoms; R4 represents hydrogen or a methyl group; and X represents hydrogen or fluorine.
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