BRAUN, Marie-Gabrielle,GARLAND, Keira,HANAN, Emily,PURKEY, Hans,STABEN, Steven T.,HEALD, Robert Andrew,KNIGHT, Jamie,MACLEOD, Calum,LU, Aijun,WU, Guosheng
申请号：
EP16762788
公开号：
EP3347361A1
申请日:
2016.09.07
申请国别(地区):
EP
年份:
2018
代理人:
摘要：
Described herein are tricyclic compounds with phosphoinositide-3 kinase (PI3K) modulation activity or function having the Formula I structure: or stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, and with the substituents and structural features described herein. Also described are pharmaceutical compositions and medicaments that include the Formula I compounds, as well as methods of using such PI3K modulators, alone and in combination with other therapeutic agents, for treating diseases or conditions that are mediated or dependent upon PI3K dysregulation.
