EICKMEIER, CHRISTIAN,SIEGER, PETER,KOERNER, VOLKMAR,HERTER, ROLF,RALL, WERNER
申请号：
EP02719831.6
公开号：
EP1362030B1
申请日:
2002.02.14
申请国别(地区):
EP
年份:
2012
代理人:
摘要：
Die Erfindung betrifft das Hydrochlorid des 4-[4-(2-Pyrrolylcarbonyl)-1-piperazinyl]-3-trifluormethyl-benzoylguanidins, Verfahren zu dessen Herstellung sowie dessen Verwendung zur Herstellung eines Arzneimittels.4-[4-(2-pyrrolylcarbonyl)-1-piperazinyl]-3-trifluoromethylbenzoylguanidine hydrochloride and its hydrates, processes for preparing this benzoylguanidine salt and its hydrates, pharmaceutical compositions containing this benzoylguanidine salt and its hydrates, and its use in treating diseases, particularly those in which inhibition of the cellular Na<；SUP>；+<；/SUP>；/H<；SUP>；+<；/SUP>； exchange is of therapeutic benefit.L'invention concerne l'hydrochlorure de 4-[4-(2-pyrrolylcarbonyl)-1-pipérazinyl]-3-trifluorométhyl-benzoylguanidine, son procédé de production et son utilisation pour produire un médicament.
