Diego Arango Del Corro,Simó Schwartz Navarro,John Martin Mariadason
申请号：
US13393215
公开号：
US20120231020A1
申请日:
2010.09.01
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The invention relates to the identification of aprataxin (APTX) expression levels as a marker for the response to topoisomerase I inhibitor-based therapies in patients with cancer and, more particularly, colon cancer. The invention also relates to methods for treating patients with cancer who have low APTX expression levels by means of administering a topoisomerase I inhibitor to said patients.
