UTILISATION DE LIGANDS DU RÉCEPTEUR DE MORT CELLULAIRE PROGRAMMÉE COUPLÉS À DES SUPPORTS SOLIDES POUR LA MULTIPLICATION DE CELLULES T RÉGULATRICES HUMAINES

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专利权人:

Northwestern University

发明人:

申请号：

EP15830251.3

公开号：

EP3177711A4

申请日:

2015.08.07

申请国别(地区):

EP

年份:

2018

代理人:

摘要：

Disclosed are methods for isolating, cultivating, and/or cells including regulatory T cells (Tregs). The methods typically include cultivating cells including Tregs in a culture media comprising a ligand for programmed cell death receptor (PD-1) conjugated to a solid support. Suitable ligands may include PD-L1 and suitable solid supports may include magnetic or paramagnetic beads where the methods further include removing the PD-L1/bead conjugates after the Tregs have been isolated, cultured, and/or expanded.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/