Use of Rheto-associated protein kinase inhibitors, pharmaceutical compositions containing Rheto-associated protein kinase inhibitors, methods of manufacture and uses of pharmaceutical compositions
The present invention is directed to Rho-associated protein kinase (ROCK) inhibitors of formula (I), pharmaceutical compositions containing said Rho-related protein kinase inhibitors, methods for their preparation and the use of ROCK for treating or preventing ROCK-mediated diseases. It is about.본 발명은 화학식 (I)의 Rho-관련 단백질 키나아제(ROCK) 억제제, 상기 Rho-관련 단백질 키나아제 억제제를 함유하는 약학 조성물, 이의 제조 방법 및 ROCK-매개성 질환을 치료 또는 예방하기 위한 ROCK의 용도에 관한 것이다.