Triazolopyridines and triazolopyrimidines that lower stress-induced p-tau

• 收藏
• 分享

专利权人:

Buck Institute for Research on Aging

发明人:

John, Varghese,Bredesen, Dale E.

申请号：

AU2016220049

公开号：

AU2016220049A1

申请日:

2016.02.17

申请国别(地区):

AU

年份:

2017

代理人:

摘要：

In certain embodiments compounds (e.g., triazolopyrimidine(s) and/or triazolopyridine(s)) are provided that are effective to lower p-tau and/or to prevent or reduce elevation of p-tau, particularly in response to stress (e.g., elevated cortisol levels). The 5 compounds are useful in the treatment or prophylaxis of pathologies characterized by abnormal amyloid plaque and or tangle formation and/or deposition.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/