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1,3-diphenylpropane derivatives, preparations and uses thereof
专利权人:
GENFIT
发明人:
JEAN-FRANÇOIS DELHOMEL,KARINE BERTRAND,MATHIEU DUBERNET
申请号:
BR112014016129
公开号:
BR112014016129A2
申请日:
2012.12.28
申请国别(地区):
BR
年份:
2017
代理人:
摘要:
1/1 Summary "1,3-diphenylpropane derivatives, preparations and uses thereof" The present invention relates to novel 1,3-diphenylpropane derivatives, pharmaceutical compositions comprising them and their therapeutic uses, in particular in the health fields human and animal. The compounds according to the present invention have intrinsic powder agonist properties. These are therefore of particular interest in the treatment of metabolic and / or inflammatory diseases, and particularly peripheral and central diseases associated with metabolic syndrome, such as various forms of steatoepatitis, type 2 diabetes, various neurodegenerative disorders, such as alzheimer's disease. , parkinson's disease and multiple sclerosis.1/1 resumo “derivados de 1,3-difenilpropano, preparações e usos destes” a presente invenção diz respeito a novos derivados de 1,3difenilpropano, composições farmacêuticas que compreendem os mesmos e os usos terapêuticos destes, em particular, nos campos de saúde humana e animal. os compostos de acordo com a presente invenção têm propriedades de agonista de ppar intrínsecas. estes são, portanto, de interesse particular no tratamento de doenças metabólicas e/ou inflamatórias e, particularmente doenças periféricas e centrais associadas com a síndrome metabólica, tais como formas diversas de esteatoepatite, diabetes tipo 2, distúrbios neurodegenerativos diversos, tais como doença de alzheimer, doença de parkinson e esclerose múltipla.
来源网站:
中国工程科技知识中心
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