ERIC F. CONNOR,GERRIT KLAERNER,JERRY M. BUYSSE,KALPESH N. BIYANI,MATTHEW J. KADE,MICHAEL J. COPE,PAUL H. KIERSTEAD,RANDI K. GBUR,SCOTT M. TABAKMAN,SON H. NGUYEN
申请号:
BR112015030142
公开号:
BR112015030142A2
申请日:
2014.06.05
申请国别(地区):
BR
年份:
2017
代理人:
摘要:
abstract pharmaceutical compositions for and methods of treating an animal, including a human, and methods of preparing such compositions. the pharmaceutical compositions contain crosslinked amine polymers and may be used, for example, to treat diseases or other metabolic conditions in which removal of protons and / or chloride ions from the gastrointestinal tract would provide physiological benefits such as normalizing serum bicarbonate concentrations and the blood ph in an animal, including a human. translation of abstract patent summary for: "proton binding polymers for oral administration." pharmaceutical compositions and methods of treating an animal, including a human, and methods of preparing such compositions. The pharmaceutical compositions contain cross-linked amine polymers and may be used, for example, to treat diseases or other metabolic conditions in which the removal of proton ions and / or gastrointestinal tract chloride may provide physiological benefits, such as normalization of bicarbonate concentrations. of serum and blood ph in an animal, for example a human.abstract pharmaceutical compositions for and methods of treating an animal, including a human, and methods of preparing such compositions. the pharmaceutical compositions contain crosslinked amine polymers and may be used, for example, to treat diseases or other metabolic conditions in which removal of protons and/or chloride ions from the gastrointestinal tract would provide physiological benefits such as normalizing serum bicarbonate concentrations and the blood ph in an animal, including a human. tradução do resumo resumo patente de invenção para: "polímeros de ligação de próton para administração oral." composições farmacêuticas e métodos de tratamento de um animal, incluindo um humano, e métodos de preparação de tais composições. as composições farmacêuticas contêm polímeros de amina reticulados e podem ser usadas, por exemplo, para tratar doenças ou outras condições metabólicas em que