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AN INDEX FOR QUANTIFICATION OF BOWMANS LAYER FOR DIAGNOSIS OF DISEASE AND PROGNOSIS OF TREATMENTS IN HUMAN CORNEA
专利权人:
发明人:
DR ABHIJIT SINHA ROY,DR ROHIT SHETTY,DR BHUJANG SHETTY
申请号:
IN6539/CHE/2015
公开号:
IN2015CH06539A
申请日:
2015.12.08
申请国别(地区):
IN
年份:
2017
代理人:
摘要:
The present invention defines a Bowman™s Refractive Index (BRI) for quantification of microdistortions in Bowman™s Layer (BL) after Small Incision Lenticule Extraction (SMILE) in patient. BRI is summation of one or more areas of the OCT image of anterior edge of Bowman™s layer, quantifies the smoothness of the Bowman™s layer. The anterior edge of Bowman™s layer is segmented into pixels. After segmentation, a 3rd order polynomial is curve fit to the segmented pixels of the edge of the Bowman™s layer. The areas enclosed in the Bowman™s layer are termed as A1, A2, A3¦¦. An and BRI is defined as BRI=_(k=1)n¦A_k=A_1+A_2++A_k Where n is the number of areas enclosed BRI is calculated by segmentation of the 3-Dimensional (3-D) OCT image. BRI acts as a marker for mechanical stability and is useful for diagnosis of disease and prognosis of treatments in human. (Figure 2)
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