A disposable or re-usable handheld, one piece device is provided for pre-drilling and application of a shape memory or elastic staple for fixation in bone surgery. Various embodiments include a one piece device that has set holes at one end to allow for pre-drilling for the shape memory or elastic staple legs and includes an application feature at the other end to disengage the shape memory or elastic staple from the one piece device. The one piece device can come in different sizes depending on the size of the shape memory or elastic staple. The one piece handheld shape memory or elastic staple holder and drill guide allows for a handheld device to accomplish both pre-drilling and application of the shape memory or elastic staple for surgical bone fixation procedures.