Disclosed herein are embodiments of a feed supplement comprising silica, mineral clay, glucan and mannans, wherein each particle of the feed supplement comprises silica, mineral clay, glucan and mannans. The feed supplement may be a granular feed supplement, and the granules may have at least one dimension between 4 mesh and 100 mesh size. In some embodiments, at least 40% of the granular feed supplement has at least one dimension greater the 100 mesh. Administration of the feed supplement to an animal may increase expression of one or more immune system biomarkers in that animal relative to animals not administered the composition.
