Compounds derived from 6 - (aryl) pirido [2,3-d] pyrimidine - 7 (8h) - One, or a Salt or N - Oxide, such as Pak inhibitors； Pharmaceutical composition that is useful for dealing with fragile X Syndrome.
AFRAXIS HOLDINGS, INC.;THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES
发明人:
DURON SERGIO G,MCKEW JOHN C,HUANG WENWEI,CAMPBELL DAVID,BEHNKE MARK,SHEN MIN
申请号：
CL2014001132
公开号：
CL2014001132A1
申请日:
2014.04.30
申请国别(地区):
CL
年份:
2014
代理人:
摘要：
Provided herein are PAK inhibitors and methods of utilizing PAK inhibitors for the treatment of cell proliferative disorders and/or CNS disorders.COMPUESTOS DERIVADOS DE 6-(ARIL)PIRIDO[2,3-D]PIRIMIDIN-7(H)-ONA, O UNA SAL O N-OXIDO DE LOS MISMOS, COMO INHIBIDORES DE PAK； SUS COMPOSICIONES FARMACEUTICA； Y USOS FARMACOLOGICOS, UTILES PARA TRATAR PARCIAL O TOTAL LA PLASTICIDAD SINAPTICA ANOMALA Y LA DEPRESION A LARGO PLAZO (DPL) ANOMALA ASOCIADA CON EL SINDROME DE X FRAGIL.
