SYSTEMES THERAPEUTIQUES A LIBERATION IMMEDIATE POUR UNE MEILLEURE ABSORPTION PAR VOIE ORALE DE LA 7-[(E)]-T-BUTYLOXYMINOMETHYLE] CAMPTOTHECINE

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专利权人:

SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A.

发明人:

LONGO, ANTONIO,PACE, SILVIA,PEDRANI, MASSIMO

申请号：

CA2612080

公开号：

CA2612080C

申请日:

2006.07.11

申请国别(地区):

CA

年份:

2013

代理人:

摘要：

A pharmaceutical composition comprising a camptothecin as active ingredient isherein described. In particular immediate-release therapeutic systems aredescribed for the improved oral absorption of 7-[(E)-t-butyloxyminomethyl]camptothecin, comprising a matrix consisting of liquid amphiphilic substancesor having a melting point lower than 60~C, in which the active principle is atleast partially dissolved and/or dispersed and/or inglobated.

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