An infusion system for infusion of a liquid into a body of a user from a reservoir, the infusion system comprises a glucose sensor; an external infusion device; and a glucose meter to generate information that is provided to the external infusion device. The external infusion device itself comprises a drive mechanism to operatively couple with the reservoir to infuse the liquid into the body, a housing to contain the reservoir, wherein the drive mechanism is contained within the housing, the drive mechanism operatively couples with the reservoir within the housing, and the housing is capable of being concealed from view on the user, a processor that uses information provided from the glucose meter, a memory to store information related to the external infusion device, a receiver used in conjunction with the processor to download glucose sensor data from the glucose sensor, and a display device to display the sensor data. The processor uses the downloaded glucose sensor data from the glucose sensor, the information from the glucose meter, and the information related to the external infusion device to assist the user in making therapy decisions.