HAN, Kyuboem,KIM, Chun-Hyung,KIM, Yu Jin,YU, Shin-Hye,KIM, Nayoung,KIM, Mi Jin,CHOI, Yong-Soo,LEE, Seo Eun
申请号：
AU2019257834
公开号：
AU2019257834A1
申请日:
2019.04.25
申请国别(地区):
AU
年份:
2020
代理人:
摘要：
Mitochondria modified by a targeting protein, according to one embodiment of the present invention, can be effectively delivered to a target. In addition, when a protein of interest bound to the modified mitochondria is delivered into a cell, various activities can be exhibited. The modified mitochondria can effectively cause cancer tissue death, and thus can also be used as an anticancer agent. Furthermore, various activities are exhibited according to a protein of interest loaded on a modified mitochondria, and thus the modified mitochondria can be applied in the treatment of various diseases. Additionally, a fusion protein comprising a protein of interest and a fusion protein comprising a targeting protein, according to one embodiment of the present invention, can be used in order to modify mitochondria. Moreover, mitochondria modified with the fusion proteins exhibits various effects in a target cell.
