The present invention provides a 3D structural electrode having high cell affinity and capacitive coupling, comprising a pillar portion and a spherical portion, wherein the diameter of the spherical portion is larger than that of the pillar portion, and the carbon nanotubes are coated on the spherical portion, and pillar portion and the spherical portion are made of material selected from metal materials. The present invention may be used for developing biological probes having high cell affinity and capacitive coupling so as to provide high accuracy for measurement of neural cells or electrocardiograms and prevent from distortion.本發明提供一種具細胞親和力與電容耦合性之立體電極,包含相互連接之柱狀部及球狀部,其中球狀部之半徑大於柱狀部之半徑,且球狀部上覆蓋有奈米碳管,其中柱狀部及球狀部之材料係選自金屬材料。本發明可用以開發具有細胞親和力、低阻抗及高電容耦合性之生物探針,有利於神經細胞或心電圖的量測準確度以避免結果失真。10‧‧‧立體電極11‧‧‧球狀部12‧‧‧柱狀部13‧‧‧奈米碳管20‧‧‧催化層30‧‧‧絕緣層40‧‧‧導電層d1、d2‧‧‧半徑
