It possesses the satisfactory food impression sense of taste inside the buccal cavity, it offers the sufficient hardness which the problem which at the same time was called to formulation process and when circulating the being lacking and degradation does not occur, and in-mouth rapidly-disintegrable tablet which possesses the satisfactory collapsibility inside the buccal cavity. Distributing the inorganic forma medicine and starch in the composite particle consisting of mannitol and kishiritoru due to spray drying, it is possible to produce in-mouth rapidly-disintegrable tablet which possesses the food impression sense of taste, hardness and the collapsibility which are superior by blendinging the constituent which becomes to in-mouth rapidly-disintegrable tablet.口腔内で良好な食感・味覚を有し、かつ製剤過程や流通時に欠けや粉化といった問題が生じない十分な硬度、及び口腔内での良好な崩壊性を有する口腔内速崩壊錠を提供する。マンニトールとキシリトールからなる複合粒子中に無機賦形剤とスターチ類を噴霧乾燥により分散してなる組成物を口腔内速崩壊錠に配合することによって、優れた食感・味覚、硬度及び崩壊性を有する口腔内速崩壊錠を製造することができる。
