TIAZOLIDINE DERIVATIVES AND METHODS FOR PREPARATION.

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专利权人:

KAINOS MEDICINE, INC.;KOREAN RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY;YUNGJIN PHARM. CO LTDA.

发明人:

SUNG SOO,JIN HEE,HYAE GYEONG,SANG DAL,NAM SOOK,KI YOUNG,SEUNG KYU,WON HOON,SUNG GYU,SUN YOUNG,JAE HONG,SANG KWON,MIN KI,NI NA

申请号：

BRPI0806592

公开号：

BRPI0806592A2

申请日:

2008.01.16

申请国别(地区):

BR

年份:

2014

代理人:

摘要：

The present invention relates to novel 2-carbonyl-3-acyl-1,3-thiazolidines having a &bgr；-amino group on the acyl chain, in free, prodrug form or pharmaceutically acceptable salt thereof, including their enantiomers, diastereomers and racemates, as efficient inhibitors against DPP-IV. The invention further relates to the pharmaceutical compositions comprising the disclosed compounds. The present invention also relates to methods for preparing the disclosed compounds and for treating DPP-IV-mediated diseases.

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