FEDERALNOE GOSUDARSTVENNOE BYUDZHETNOE UCHREZHDENIE "ROSSIJSKIJ NAUCHNYJ TSENTR RADIOLOGII I KHIRURGICHESKIKH TEKHNOLOGIJ IMENI AKADEMIKA A.M. GRANOVA" MINISTERSTVA ZDRAVOOKHRANENIYA ROSSIJSKOJ FEDERA
发明人:
Popov Sergej Aleksandrovich (RU),Попов Сергей Александрович (RU),Sklyar Dmitrij Aleksandrovich (RU),Скляр Дмитрий Александрович (RU),Statsenko Andrej Anatolevich (RU),Стаценко Андрей Анатольевич (RU)
申请号：
RU2019124142
公开号：
RU0002706347C1
申请日:
2019.07.24
申请国别(地区):
RU
年份:
2019
代理人:
摘要：
FIELD: medicine.SUBSTANCE: invention refers to medicine, particularly to a method of treating operable pancreatic head adenocarcinoma. Method of treating operable pancreatic adenocarcinoma, including intra-arterial administration of chemotherapeutic agents Abraxane and gemcitabine, wherein the chemopreparations are additionally oxaliplatin, which is introduced through a catheter inserted into a gastroduodenal artery, infusion, then bolus Abraxane, performing selective tumor embolization, after which the catheter is reinserted into the celiac and the gemcitabine is infused, not earlier than one day after the chemotherapy, sessions of the conformal radiation therapy are performed； surgical removal of the tumor is performed not earlier than the day after the end of the radiation therapy, after which no earlier than 2 weeks later infusion of gemcitabine is introduced into a cogwheel, then no later than 4 weeks, systemic adjuvant chemotherapy is performed by oral administration of capecitabine and simultaneous intravenous administration of gemcitabine, implementing such administration of these preparations for not more than 4 months or until occurrence of undesired phenomena of II-III degree or progression of tumor process according to RECIST criteria, taken in certain proportions and under certain conditions.EFFECT: method described above provides improved clinical results in patients with operable pancreatic head adenocarcinoma in the form of an increase in the recurrence-free period and overall survival of the patients.1 cl, 1 exИзобретение относится к медицине, а в частности к способу лечения операбельной аденокарциномы головки поджелудочной железы. Способ лечения операбельной аденокарциномы поджелудочной железы, включающий внутриартериальное введение химиопрепаратов абраксана и гемцитабина, причем в качестве химиопрепаратов дополнительно используют оксалиплатин, который вводят через катетер, установленный в гастродуоденальную артерию, инфузионно, затем болюсно абрак
