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Polymer systems for lung volume reduction therapy
专利权人:
Alexander Schwarz;Larry W. Tsai;Edward P. Ingenito
发明人:
Edward P. Ingenito,Alexander Schwarz,Larry W. Tsai
申请号:
US12443021
公开号:
US08361484B2
申请日:
2007.09.27
申请国别(地区):
US
年份:
2013
代理人:
摘要:
One aspect of the invention relates to a hydrogel comprising a polymer comprising a plurality of pendent hydroxyl groups, a crosslinker, and a sclerosing agent. Another aspect of the invention relates to a method for reducing lung volume in a patient comprising the steps of advancing into a region of a patient's lung via said patient's trachea a multi-lumen catheter lumen through a bronchoscope; and co-administering, through the multi-lumen catheter, a first mixture comprising a first amount of a polymer containing a plurality of pendent hydroxyl groups; a second mixture comprising a second amount of a crosslinker; and a third mixture comprising a third amount of a sclerosing agent; thereby forming a hydrogel in said region. In certain embodiments, the compositions and methods described herein are intended for use in the treatment of patients with emphysema of the lung.
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中国工程科技知识中心
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