Alexander Schwarz;Larry W. Tsai;Edward P. Ingenito
发明人:
Edward P. Ingenito,Alexander Schwarz,Larry W. Tsai
申请号：
US12443021
公开号：
US08361484B2
申请日:
2007.09.27
申请国别(地区):
US
年份:
2013
代理人:
摘要：
One aspect of the invention relates to a hydrogel comprising a polymer comprising a plurality of pendent hydroxyl groups, a crosslinker, and a sclerosing agent. Another aspect of the invention relates to a method for reducing lung volume in a patient comprising the steps of advancing into a region of a patient's lung via said patient's trachea a multi-lumen catheter lumen through a bronchoscope； and co-administering, through the multi-lumen catheter, a first mixture comprising a first amount of a polymer containing a plurality of pendent hydroxyl groups； a second mixture comprising a second amount of a crosslinker； and a third mixture comprising a third amount of a sclerosing agent； thereby forming a hydrogel in said region. In certain embodiments, the compositions and methods described herein are intended for use in the treatment of patients with emphysema of the lung.
