PROBLEM TO BE SOLVED: To provide a pharmaceutical composition for treating deep vein thrombosis, which comprises an inhibitor of Bruton's tyrosine kinase (Btk). SOLUTION: (E)-4-(6-amino-9-(3-(4-(dimethylamino)-N-methylbut-2-enamido)phenyl)-8-oxo-8,9-dihydro-7H -Purin-7-yl)-N-(pyridin-2-yl)benzamide and other compounds. [Selection diagram] None【課題】ブルトン型チロシンキナーゼ（Ｂｔｋ）の阻害剤を含む深部静脈血栓症の処置のための医薬組成物の提供。【解決手段】（Ｅ）－４－（６－アミノ－９－（３－（４－（ジメチルアミノ）－Ｎ－メチルブト－２－エナミド）フェニル）－８－オキソ－８，９－ジヒドロ－７Ｈ－プリン（ｐｕｒｉｎ）－７－イル）－Ｎ－（ピリジン－２－イル）ベンズアミド等の化合物。【選択図】なし
