MILICH, DAVID R.,WHITACRE, DAVID C.,SCHICKLI, JEANNE H.
申请号：
CA2906770
公开号：
CA2906770A1
申请日:
2014.03.14
申请国别(地区):
CA
年份:
2014
代理人:
摘要：
The present disclosure generally relates to immunogens for eliciting an antibody response against respiratory syncytial virus (RSV). More specifically, the present disclosure relates to virus-like particles (VLPs) including a RSV F protein epitope, as well as methods of use thereof. Respiratory syncytial virus (RSV) is a major cause of lower respiratory tract disease in infants and young children (Hall et al., NEJM, 360:5888-598, 2009； and Nair et al., Lancet, 375:1545-1555, 2010) and a vaccine to protect this young population is of high priority.
