Michael Ochse,Udo Lange,Wilfried Braje,Berthold Behl,Wilfried Hornberger,Mario Mezler,Wilhelm Amberg,Charles W. Hutchins
申请号:
US12933326
公开号:
US08653100B2
申请日:
2009.03.31
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The present invention relates to tetrahydroisoquinoline of the formula (I)or a physiologically tolerated salt thereof.The invention relates to pharmaceutical compositions comprising such tetrahydroisoquinolines, and the use of such tetrahydroisoquinolines for therapeutic purposes. The tetrahydroisoquinolines are GlyT1 inhibitors.