GOLDHAWK, DONNA E.,KOROPATNICK, D. JAMES,FIGUEREDO, RENE,PRATO, FRANK S.,THOMPSON, R. TERRY,GELMAN, NEIL
申请号：
CA2940654
公开号：
CA2940654A1
申请日:
2014.07.08
申请国别(地区):
CA
年份:
2015
代理人:
摘要：
The invention provides an improved modified magnetosome that contains more iron therein with the combination of the expressed genes. This is achieved by co-expression of (a) one or more bacterial magnetotactic genes to amplify iron uptake, compartmentalization and biomineralization in cells, with (b) one or more mammalian iron handling proteins that together augment(s) and/or regulate the cells iron pool. As a result, mammalian cells or bacterial cells that are transfected or transformed, respectively, can be more effectively tracked using various imaging technologies.
