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新規レスベラトロール誘導体
专利权人:
UHA MIKAKUTO CO LTD
发明人:
DOI SATOSHI,土井 聡,MATSUKAWA TAIJI,松川 泰治,KUZUMI AKINOBU,來住 明宣,NOJIMA MASATOMO,野島 正朋,MATSUI TAKEKI,松居 雄毅,YAMADA YASUMASA,山田 泰正,YAMADA ICHIRO,山田 一郎
申请号:
JP2011014482
公开号:
JP2012153653A
申请日:
2011.01.26
申请国别(地区):
JP
年份:
2012
代理人:
摘要:
PROBLEM TO BE SOLVED: To provide an anti-cancer agent, a hypotensive agent, a cardiovascular disease therapeutic agent, a glucose absorption inhibitor and a diabetes preventive agent.SOLUTION: The resveratrol derivative is represented by formula (1). The new resveratrol derivative or its pharmaceutically acceptable salt, ester or ether is excellent in anti-cancer activity, particularly, in anti-oral cancer activity compared with resveratrol, ferulic acid, the already-known resveratrol derivative and luteolins, and thus it is useful as a new anti-cancer agent. Further, it has excellent angiotensin-converting enzyme inhibitory activity compared with resveratrol and flavonoid glycoside, and further has &alpha-glucosidase inhibitor activity, and thus, it is useful as new hypotensive drug, cardiovascular disease therapeutic agent, glucose absorption inhibitor and diabetes preventive agent.COPYRIGHT: (C)2012,JPO&INPIT【課題】抗癌剤、血圧降下剤、心血管病治療剤、糖吸収抑制剤、糖尿病予防剤の提供。【解決手段】式(1)のレスベラトロール誘導体。【選択図】図1
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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