Methods of using OX40 ligand encoding polynucleotides

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专利权人:

ModernaTX; Inc.

发明人:

Joshua P. Frederick,Ailin Bai

申请号：

US16207575

公开号：

US10379767B2

申请日:

2018.12.03

申请国别(地区):

US

年份:

2019

代理人:

摘要：

The disclosure relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotide molecules comprising an mRNA encoding an OX40L polypeptide. Also provided is a method for activating T cells or increasing the number of NK cells in a subject in need thereof.

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