Suzette Veronica Van Der Waal,Stanley Brul,Johannes Jacob De Soet,Lucas Wilhelmus Maria Van Der Sluis
申请号：
US13579577
公开号：
US08808718B2
申请日:
2011.02.18
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The present invention concerns a disinfectant or antimicrobial composition for use in dental treatment, such as treatment and/or prevention of periodontitis, gingivitis or other forms of oral infection. The present Inventor found that microorganisms that infect the dental tissues and cause inflammation thereof, are susceptible to osmotic stress, to such extent that the application of a hypertonic composition is effective in curing or preventing infection and/or inflammations. It was furthermore found that these microorganisms are also susceptible to acidic stress. The present invention therefore provides compositions that induce osmotic stress in microorganisms causing infection of dental tissue when topically applied thereto, preferably osmotic as well as acidic stress. The present invention also concerns the methods and uses involving the compositions of the invention.
