YONSEI UNIVERSITY;INDUSTRY-ACADEMIC COOPERATION FOUNDATION
发明人:
Jong Hyuk SUNG,Na Hyun CHOI
申请号：
US16427084
公开号：
US20190367879A1
申请日:
2019.05.30
申请国别(地区):
US
年份:
2019
代理人:
摘要：
The present invention relates to a hair growth-inducing ability enhancing effect of adipose stem cells obtained by performing treatment with udenafil and performing culture, and provides a composition for preventing or treating alopecia, or promoting hair growth, comprising, as an active ingredient, adipose stem cells obtained by performing treatment with udenafil and performing culture, IL-4, or IL-12B. In a case where a culture medium of adipose stem cells is treated with udenafil and cultured, IL-4 and IL-12B expression levels are increased in the adipose stem cells, and thus maturation of hair follicle cells is further promoted, so that hair growth can be induced. In addition, in a case where IL-4 and IL-12B, which are expressed in the adipose stem cells obtained by performing treatment with udenafil and performing culture, are applied to skin tissue, hair growth can be induced.
