Oliver Plettenburg;Matthias Löhn;Olivier Duclos;Jochen Goerlitzer;Fréderic Jeannot;Katrin Lorenz;Sandrine Biscarrat
发明人:
Oliver Plettenburg,Katrin Lorenz,Jochen Goerlitzer,Matthias Löhn,Sandrine Biscarrat,Fréderic Jeannot,Olivier Duclos
申请号:
US12487503
公开号:
US08710077B2
申请日:
2009.06.18
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The invention relates to 6-substituted isoquinoline and isoquinolinone derivatives of the formula (I)useful for the treatment and/or prevention of diseases associated with Rho-kinase and/or Rho-kinase mediated phosphorylation of myosin light chain phosphatase, and compositions containing such compounds.