Charles S. Springer, Jr.,Wei Huang,Xin Li,William D. Rooney, Jr.,Ian J. Tagge,James A. Balschi,Yajie Zhang
申请号:
US14395785
公开号:
US20150087967A1
申请日:
2013.04.22
申请国别(地区):
US
年份:
2015
代理人:
摘要:
Provided herein is a Magnetic Resonance Imaging (MRI) technique and, optionally, software, collectively referred to as the “shutter-speed” model, to analyze image data of cancer patients. Embodiments provide a minimally invasive, yet precisely accurate, approach to determining whether tumors are malignant or benign by distinguishing the characteristics of contrast reagent activity in benign and malignant tumors. Exemplary embodiments provide MRI measured biomarkers for tumor malignancy determination and monitoring, effectively eliminating or limiting the false positives suffered by existing MRI techniques while also improving tissue phenotyping and therapeutic intervention monitoring and prediction.