A one-way valve device, in particular a low-pressure check valve, for use in infusion equipment, with a housing having an inlet line and an outlet line, the inlet and outlet lines being connected to a pressure space in the housing, the inlet line being arranged on a first side of the housing, and the outlet line being arranged on a second side of the housing opposite the first side, the pressure space being constructed from two interconnected pressure chambers, and the one-way valve device being designed such that the through-flow is interrupted by a static underpressure prevailing on the inlet line and/or the outlet line or by an overpressure on the outlet line, wherein the two pressure chambers are arranged lying one above the other in the housing with respect to the flow direction between the first and the second side.