Daniela Alberati,Luca Gobbi,Matthias Koerner,Bernd Kuhn,Jens-Uwe Peters,Rosa Maria Rodriguez-Sarmiento,Mark Rogers-Evans,Markus Rudolph
申请号:
US12626982
公开号:
US08178538B2
申请日:
2009.11.30
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention is concerned with novel pyridazinones of formula (I)wherein R1, R2, R3 and R4 are as defined in the description and in the claims, as well as physiologically acceptable salts and esters thereof. These compounds inhibit PDE10A and can be used for the treatment of CNS disorders.