SELECTIVE AGONIST OF TOLL-LIKE RECEPTOR 3

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专利权人:

HEMISPHERX BIOPHARMA; INC.

发明人:

CARTER, WILLIAM, A.,STRAYER, DAVID

申请号：

EP09710652

公开号：

EP2249845A4

申请日:

2009.02.17

申请国别(地区):

EP

年份:

2012

代理人:

摘要：

A mismatched double-stranded ribonucleic acid, which is an agonist for Toll-like receptor 3 (TLR3), is used in vitro or in vivo as an antimicrobial agent, antiproliferative agent, and/or immunostimulant. Poly(l:C11-14U) is a more selective agonist of TLR3 as compared to poly(l:C) even though the both double-stranded RNA are structurally analogous.

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