Christina Yamada,Anastasia Khvorova,Robert J. Kaiser,Emily Anderson,Devin Leake
申请号:
US13552709
公开号:
US20120322855A1
申请日:
2012.07.19
申请国别(地区):
US
年份:
2012
代理人:
摘要:
Provided herein are duplex oligonucleotide complexes which can be administered to a cell, tissue or organism to silence a target gene without the aid of a transfection reagent(s). The duplex oligonucleotide complexes of the disclosure include a conjugate moiety that facilitates delivery to a cell, tissue or organism.