The present technology relates to a medical support device, a method thereof, and a medical support system, which make it possible to notify of more various events.In the present technology, an event in a living body is detected on the basis of change in time of temperature of a surgical site or around the surgical site, and notification information notifying according to the detected event in the living body is generated. The present technology may be applied to, for example, the medical support device, an endoscope device, a microscope device, a computer controlling the devices, or a medical support system including a plurality of devices and the like.