Timothy P. Tully,Roderick E.M. Scott,Rusiko Bourtchouladze
申请号:
US13305008
公开号:
US20120094916A1
申请日:
2011.11.28
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention provides methods for screening a pharmaceutical agent for its ability to modulate long term memory formation, performance of a hippocampal-dependent cognitive task or STAUFEN function. The present invention also provides methods for modulating long term memory formation or performance of a hippocampal-dependent cognitive task by modulating staufen-dependent protein expression. The present invention further provides methods for treating a defect in long term memory formation associated with a defect in STAUFEN and methods for treating a defect in performance of a hippocampal-dependent cognitive task associated with a defect in STAUFEN.